South Sudan: Cholera Outbreak Situation Report No. 74 (Reporting date: 28 April 2026)

Country: South Sudan Sources: Health Cluster, World Health Organization Please refer to the attached file. Key Weekly Highlights as of 27 April 2026 • In the past week, 189 new suspected cases and 1 death (CFR: 0. 5%) were reported across 6 counties, a 1% reduction from the cases reported last week (191 cases) • In the last 14 days of reporting (onset from 14 April 2026 to 27 April 2026), 600 new cases and 4 deaths (CFR: 0. 7%) were reported in 8 counties. Most of these cases came from Mayom (390, 65. 0%), Panyijiar (104, 17. 3%), Ayod (55, 9. 2%) and Awerial (24, 4. 0%). • From 28 September 2024 to 27 April 2026, 103, 195 cases, including 1, 669 deaths have been reported in 55 counties, across 9 states and all three administrative areas (i. e. , Abyei, Ruweng and Greater Pibor). • Of the 1, 669 deaths, 834 (50. 0%) occurred in health facilities, while the rest were community deaths. The overall case fatality rate (CFR) is 1. 6%, while the health facility CFR is 0. 8%. • Unity State continue to account for the highest burden of cholera cases at 33% (34, 291) followed by Jonglei State at 15% (15, 314) and Central Equatorial State at 12% (12, 794) of the cumulative cases. • The age group with highest case count is 0-4 years (24%) followed by those aged 5-14 years (22%). • Mayom and Panyijiar are the only counties in Unity state still reporting cholera cases. • The outbreak is now geographically limited to five states: Jonglei, Unity, Lakes, Central Equatoria, and Upper Nile, largely driven by conflict and poor WASH conditions especially among displaced and returnee/refugee populations.

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