Malaria Persistence in South Sudan: Ups and Down (World Malaria Day – 2026)

Country: South Sudan Source: World Health Organization Please refer to the attached file. 348/1000 Malaria incidence rate 22% IPTp Rate 62% ITN Usage BACKGROUND INFORMATION South Sudan remains a high malaria burden country within the High Burden to High Impact (HBHI) countries, with malaria continuing to be the leading cause of morbidity and mortality despite expanded interventions. The disease accounts for a significant share of outpatient visits and inpatient deaths, with transmission characterized by seasonal peaks, persistent hotspots, and periodic resurgences. MALARIA BURDEN AND TRANSMISSION Analysis of confirmed malaria cases in South Sudan shows a persistently high burden, with malaria accounting for over 38% of outpatient visits and ~64% of inpatient deaths in 2025. Transmission remains perennial with seasonal peaks following the rainy season, and malaria incidence has increased from 246 cases per 1, 000 population in 2021 to over 400 per 1, 000 in 2024, with deaths closely mirroring case trends. Although overall case numbers remain high, incidence mapping reveals localized hotspots, underscoring geographic variation in transmission risk and the need for targeted interventions.

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